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DO YOU KNOW?-3

DO YOU KNOW?-3
CREATININE CHEMISTRY

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Saturday 24 October 2020

A Cartoon Analogy to Explain Protein Synthesis in Eukaryotes:-

 CENTRAL DOGMA IN EUKARYOTES-CARTOON ANALOGY

A CARTOON ANALOGY

The transcription and the translation, the two major phases of the Central Dogma of a eukaryotic cell can be made easy and simplified to understand with the above shown analogous cartoon figure.
In the eukaryotes, unlike in the prokaryotes, the transcription phase occurs within the nucleus.
It is analogous to taking a copy of a particular cooking recipe from the original cookery guide book.
The original cookbook is the entire DNA chain embossed in the chromosome strand.
The particular page that contains the recipe to be transcribed is a gene portion of the DNA strand.
The copy making machine is the enzyme, DNA dependent  RNA Polymerase (RNAP).
The transcribed raw copy before the proofreading is the immature mRNA.
The proof-reader is the snRNA
After the proofreading (splicing) the matured mRNA swim out from the nucleus into the cytosol for translation.
The translation phase occurs in the cytosol.
In translation, there are many types of utensils that fit to bring suitable raw material to the cooker.
The utensils are the tRNAs
The raw materials are the amino acids
The cooker is the ribosome
The finished product is the protein molecule.
 


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