ANTI DEPRESSANTS-Contd...
Atypical Antidepressants:
Atypical antidepressants do not have a specific class of action but their antidepressant effects are most probably by an unknown mechanism with minimum side effects.
1.Trazadone:-
An antidepressant is structurally very similar to the benzodiazepine alprazolam but more specific in the inhibition of serotonin reuptake.
It is particularly effective in improving sleep.
It is metabolized in the liver and excreted by the kidneys.
Side Effects
1.Sedation
2.Orthostatic hypotension
3.Nausea
4.Headache and dizziness
5.Agitation
6.Anticholinergic effects(Rare)
2.Bupropion
It is also an atypical antidepressant with an unclear mechanism of action.
Side Effects
1.Headache
2.Nausea
3.Tachycardia
4.Restlessness
Fortunately, with bupropion there is no sexual dysfunction toxicity which is distinctive with SSRIs.
SSRI:-Serotonine Specific Reuptake Inhibitor
