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DO YOU KNOW?-3

DO YOU KNOW?-3
CREATININE CHEMISTRY

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Tuesday 28 November 2017

IMPORTANT MEDICAL BITS

SOME USEFUL BITS
1.WARFARIN PREVENTS CANCER
Recent research has proved that the anticoagulant warfarin which is used for cardiovascular problems such as arrhythmias, stroke, and heart attacks can also be used to prevent the formation of cancer cells. This is acted by blocking AXL receptor tyrosine kinase and thereby inhibiting a vitamin-K dependant protein known as G.A.S-6.   This G.A.S-6 is a Growth Stop (or suppress) Specific gene coding protein. It is a gamma-carboxy glutamic acid domain-containing protein. Warfarin inhibits this gene coding protein and thereby blocking the spreading of cancer cells.

2.CREATININE

Creatinine is a metabolic waste of an amino acid called creatine. Low creatinine level is a matter of concern. Creatine is an amino acid formed from the body muscle and from the food. The body uses creatine as energy. Decreased creatinine levels in the blood indicate muscle weakness, underweight, and liver problems. But a decreased level of blood-creatinine is normal in the older age and lean body.

3.SUGAR DRINKS

Doctors warn that just two sugary drinks per week may considerably increase blood sugar to a level of concern.

4. TEEN MOTHERS AT RISK 

The American Heart Association in their journal has published an article. In that article, they said that women who become mothers for the first time at their teenage are at higher risks of getting heart diseases. But there are fewer risks if a woman attains their first motherhood at normal old age.

5.DIABETIC ITCHING

It is not necessarily only diabetes may cause itching. There may be other reasons but diabetes can surely produce severe itching particularly on hands and feet.
The main reason is high blood glucose levels will damage peripheral nerves which leads to diabetic polyneuropathy. Before the nerve damage occurs there are high secretions of cytokines which are inflammatory substances will lead to itching and reddening of the skin particularly at hands and feet

6.ANTIBIOTIC DANGERS

A piece of recent research information has warned that there are wrong uses of antibiotics that are rising to dangerous levels. Because of this even a powerful antibiotic like colistin becomes resisted by most of the gram-negative bacteria. India tops first in the consumption of antibiotics followed by China and the U.S.

7. SOYBEANS INCREASES THE RISK OF ADVANCED PROSTATE CANCER

 Eating soy meal is a favorite regular food but it looks not good for men. According to recent research the components of the soy known as Isoflavones produce advanced prostate cancer. These isoflavones are estrogen-like compounds. Hence they may produce negative effects on men.

8.HARD AND BRISK WALKING - GOOD FOR AGED WOMEN

 Women who took hard exercises such as brisk walking may increase their life span more when compared with those who are not so active. A U.S.research team has found out that.

9.BLOOD FLOW AND MEMORY POWER

A study led by researchers of Vanderbilt University, in Nashville, Tennesee has shown that older adults with low blood flow from the heart are tied to reduced brain blood flow which will affect their memory power. 

10. INSOMNIA IDENTITY MAY HARMS MORE THAN INSOMNIA

Recent sleep research by the psychiatrist Kenneth Lichstein, professor of psychology at the University of Alabama in Tuscaloosa reveals that worrying insomnia dos more harmful effects to the body than insomnia itself. Hence do not worry about insomnia. Take it sportively.


Wednesday 15 November 2017

SOME FACTS ON ALCOHOL

ALCOHOL-SOME FACTS

Let us see how our body handles alcohol soon after its consumption.
Immediately after consumption alcohol passes through the liver as the first pass to be metabolized.
The liver can metabolize one ounce of alcohol per hour
After consumption alcohol can remain in the blood for several hours and in the urine for several days 
After consumption, approximately 20% of alcohol is absorbed by the stomach and the remaining 80% absorbed by the small intestine
Any remainder portion left is excreted out by saliva, sweat, and urine.
After absorption into the bloodstream alcohol goes to the liver. The liver produces enzymes to process alcohol.
But if someone is drinking alcohol rapidly the liver cannot process all alcohol and hence some alcohol may remain in the body without metabolized.
The total amount of unprocessed alcohol remained in the blood is known as Blood Alcohol Concentration (BAC)
The higher the BAC the more pronounced effects as follows.

Pronounced Alcoholic Effects

1.Reduced Inhibitions
2.Damaged Memory
3.Slurred Speach
4.Confusion
5.Difficult concentration
6.Respiratory depression
7.Vomiting
8. Impaired Balance and Coordination
9.Irritability

Age

Age influences the alcoholic usage by retaining alcohol longer time in the liver in old aged people.
The reasons are probably due to the slow blood flow in the old aged people and may be due to the intake of more medicines in old age which may interfere with the alcoholic metabolism in the liver.
As the liver process the alcohol at a smaller rate which increases the amount of unprocessed alcohol absorbed in the body.

Sex

Though it is not common to all, alcohol remains a long time in women's body than men's because the body of women have more fat and lesser water than the body of men.

Race

Some East Asian Race people lack the enzyme necessary to break down the alcohol molecule which leads to facial flushing, nausea, dizziness, tachycardia, and headache.

Family History 

Even though gene alone may not influence alcohol individual consumption but researches have shown that gene along with the environment may affect the alcohol handling of the body.

Body Mass Index

Similar to other drugs alcoholic metabolism may be influenced by body size
A person with a lean body or smaller BMW will have a sooner effect than the person with a larger BMW.

Medicines That Influence Liver Processing Of Alcohol

Medicines that can influence alcohol metabolism are as follows:-
1.Anxiolytics like benzodiazepines, barbiturates, meprobamate
2.Antidepressants such as amitriptyline
3.Antibiotics
4.Antihistamines
5.Antidiabetic drugs

How long does the alcohol stay in the system 

1.Blood
Measurement of BAC is one of the techniques to determine how long alcohol stays in the body.
In general alcohol is eliminated 0.015 per hour. For example if a person has a BAC of 0.08 which may be illegal to drive, it will take around 5.5 hours to flush out the alcohol from his body.
It is important to note that since alcohol is absorbed by the stomach also a person who drinks alcohol in a larger amount in an empty stomach may take even more than 24 hours to flush out the alcohol from his body.

2.Urine

The latest and more sensitive urine tests have proved that alcohol can be present in the urine up to 80 hours or up to 3 to 4 days after the last drink.

3.Breath

The most sensitive tests have proved that alcohol can be present in the breath up to 24 hours after the last drink.

4.Hair

Hair tests have proved that alcohol can be detected in the hair up to 90 days after last drink

5.Saliva

Tests have proved that traces of alcohol can be detected in the saliva up to 24 hours after the last drink.

6.Breast Milk

It is proved that alcohol is present in the breast milk as long as its presence in the blood. When it leaves from the blood automatically it would leave from the milk, hence it is not necessary to pump the milk from the breast to clear alcohol.

Long term effects of Drinking

Heavy drunkards may have the following risks
1.Cancer of the mouth, throat, and breast
2.Stroke
3.Heart problems
4.Liver damage
5.Nervous and brain damages

Conclusion 

Alcohol becomes a social drink in parties and in recreation clubs.
Frequent social drinking habit is risky. If anyone feels he drinks alcohol frequently to become a stage of heavy drink without control should speak with their doctor.

 



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