A GENE THAT CAUSES DM
Type 2 diabetes the most common type of DM affecting 90% of the people in which either the beta cells of the pancreas are unable to produce insulin or the body cannot utilize or respond to the insulin.
Now a research team from the UK has discovered a gene that causes the destruction of the beta islets of Langerhans that produces insulin that contributes to producing type-2 DM.
By blocking the gene TNFR5 halted the destruction process, a discovery that leads to new hope in the treatments of Type-2 DM.
The research team was lead by Dr.Mark Tuner of the School of Science and Technology, at Nottingham University in the UK.
They say that it is certain that a long time use high fat and high sugar diet can worsen the destruction of beta islet cells in Type-2 DM people with uncleared reasons.
But, now they cleared it after research with a number of genes they found that the gene TNFR-5 had the highest sensitivity to glucose and fatty acids and overexpression of this gene in response to the high fat and sugar diet leads to the development of type 2 DM.
Hence they said blocking this gene halted he destruction according to their Laboratory tests.
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