TRYCYCLIC ANTIDEPRESSANTS OVERDOSE
Amitriptylin
Tricyclic antidepressants are prescribed by many doctors to treat depressions. They are classified into secondary amines and tertiary amines. Among this amitriptyline is one of the tertiary amines available in the market by the name of Tryptizol, Tryptomer, and Elavil, etc.
Many people are using this drug under any one of the above trade names for their depressive episodes. The following ECG image can reveal how this drug is affecting your heart.
The main effect of amitriptyline on the heart is QT prolongation and a fast heartbeat. See in Fig 1 above the QRS complex is widened in a manner to embed the T-wave so that the QT-interval is elevated and prolonged.P-Q interval also prolonged.
Many people are using this drug under any one of the above trade names for their depressive episodes. The following ECG image can reveal how this drug is affecting your heart.
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| Fig-1 |
DOXEPIN:-
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| Fig-2 |
Doxepin is another tertiary amine very similar to amitriptyline. In Fig-2 the effect of doxepin is shown with a similar pattern of ECG changes to that of amitriptyline. Generally all tricyclic antidepressants produce similar patterns of ECG changes. They produce ventricular tachycardia with prolonged QT-interval.
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